喜树的化学成分和生物活性研究概况

黄石麟,孙莲莉,章燕珍,张琳,杨峻山*

中国药学杂志 ›› 2013, Vol. 48 ›› Issue (13) : 1048-1051.

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中国药学杂志
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中国药学杂志 ›› 2013, Vol. 48 ›› Issue (13) : 1048-1051. DOI: 10.11669/cpj.2013.13.003
综 述

喜树的化学成分和生物活性研究概况

  • 黄石麟1,孙莲莉2,章燕珍2,张琳2,杨峻山3*
作者信息 +

Development of Chemical Constituents and Bioactivities of Camptotheca acuminate

  • HUANG Shi-lin1, SUN Lian-li2, ZHANG Yan-zhen2,ZHANG Lin2, YANG Jun-shan3*
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文章历史 +

摘要

目的 对喜树的化学成分及其生物活性进行综述,推动我国特有树种喜树的深入研究,综合利用资源,进一步开发利用喜树提供参考。 方法 查阅国内外相关文献,进行分析、归纳和综述。结果与结论 喜树的化学成分主要是生物碱类、鞣花酸类、黄酮类和其他类型化合物,喜树提取物具有抗肿瘤、免疫抑制和抗病毒等多种生物活性。

Abstract

Objective To review the chemical constituents from Camptotheca acuminate Decne and report bioactivities, which provides detailed information for further investigations and applications of C. acuminate, a plant resource endemic to China. Methods Based on 39 domestic and foreign literatures, the analysis, induction and summarization of chemical constituents and bioactivities of C.acuminate. Results AND Conclusion The major chemical components of C. acuminate are alkaloids, ellagic acid, and flavonoids. The crude extract of C. acuminate shows anti-tumor, immunosuppression and anti-virus activities.

关键词

喜树 / 生物碱类 / 鞣花酸类 / 黄酮类 / 抗肿瘤 / 免疫抑制 / 抗病毒

Key words

Camptotheca acuminate / alkaloid / ellagic acid / flavonoid / anti-tumor / immunosuppression / anti-virus

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黄石麟,孙莲莉,章燕珍,张琳,杨峻山*. 喜树的化学成分和生物活性研究概况[J]. 中国药学杂志, 2013, 48(13): 1048-1051 https://doi.org/10.11669/cpj.2013.13.003
HUANG Shi-lin, SUN Lian-li, ZHANG Yan-zhen,ZHANG Lin, YANG Jun-shan*. Development of Chemical Constituents and Bioactivities of Camptotheca acuminate[J]. Chinese Pharmaceutical Journal, 2013, 48(13): 1048-1051 https://doi.org/10.11669/cpj.2013.13.003
中图分类号： R284   

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基金

国家重大新药创制项目(2012ZX09120201-010);浙江省自然科学基金资助项目(Y2090675)

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